The novel is based on the author's life experience who was a doctor like the main character of the book the young doctor Mason who start his career in the coal mining parts of South Wales facing ill will, hardships, bad and primitive circumstances or conditions, indifference and narrow mindness of the people and authorities. He finds the love and soul mate of his life in Christine who marries him. He even becomes a research physicist with the aim of improving the health of coal miners but the bureaucracy brings him to a dead end having to leave research for his private praxis. Soon his succesful praxis faces him with moral dilemmas and moral bankruptcy he realizes that he and his popular doctor colleagues act like charlatans and just want to take the patient's money. The Citadel by A. J. Cronin at Amazon.
The Citadel was adapted into a movie in 1938 by King Vidor. You can watch it online at youtube at the given link.
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